Management of acute bacterial rhinosinusitis
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Published on: January 17, 2018
Dennis A Conrad1, Hal B Jenson
1Department of Pediatrics, Division of Infectious Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA. conradd@uthscsa.edu
Insights
Acute bacterial rhinosinusitis in children is diagnosed clinically based on specific symptoms like persistent cough and purulent nasal discharge. High-dose amoxicillin is the recommended initial treatment for this common sinus infection.
Area of Science:
- Pediatrics
- Infectious Diseases
- Otolaryngology
Background:
- Acute bacterial rhinosinusitis (ABRS) affects the nasal epithelium and paranasal sinus mucosa in children.
- Common causative agents include Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
Purpose of the Study:
- To outline the clinical diagnosis and management of acute bacterial rhinosinusitis in pediatric patients.
- To emphasize appropriate initial pharmacotherapy and treatment duration.
Main Methods:
- Clinical diagnosis based on characteristic symptoms such as prolonged cough and purulent rhinorrhea.
- Radiographic evaluation is generally not indicated for diagnosis.
- CT scans are reserved for persistent or complicated cases.
Main Results:
- Diagnosis relies on symptoms lasting at least 10 days, often with worsening after initial cold symptoms.
- Facial pain, headache, and fever can also be present.
- Complications of ABRS in children are infrequent.
Conclusions:
- High-dose amoxicillin (80-90 mg/kg/day) is the recommended first-line therapy.
- Treatment duration is typically 10-14 days, continuing for 7 days post-symptom improvement.
- Prompt and appropriate treatment is crucial for managing pediatric ABRS.
Abstract:
Acute bacterial rhinosinusitis is an infection of the nasal epithelium and paranasal sinus mucosa, usually caused in children by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and, less frequently, group A Streptococcus species. The clinical diagnosis is based on daytime cough that may be worse at night or purulent rhinorrhea, or both, lasting at least 10 days, often worsening after a period of initial improvement after initial symptoms of the common cold, and often associated with facial or dental pain, facial fullness, or swelling, headache, and fever. Sinusitis is diagnosed clinically; radiographic evaluation is not indicated for diagnosis. When the disease persists despite treatment, or is complicated by potential intracranial or orbital extension, CT is the preferred imaging modality. Initial therapy should be amoxicillin in a high dosage (80-90 mg/kg/day). Treatment is generally for 10 to 14 days and for at least 7 days beyond the time of substantial improvement in symptoms. Complications of acute bacterial rhinosinusitis in children are rare.
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