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[Determination of malondialdehyde level in peritoneal fluid in patients with acute abdomen]
Sahin Budak1, Tanju Acar, Sevki Karakayali
1Dr. Muhittin Ulker Acil Yardim ve Travmatoloji Hastanesi Balgat/Ankara.
Background:
Our aim is to determine the relationship between free oxygen radicals and tissue destruction in Acute abdomen patients.
Methods:
In this study, direct determination of free oxygen radicals is succeeded by measuring the Malondialdehyde level (MDA), which is the last product of lipid peroxidation in the peritoneal fluid of acute abdomen patients. Forty patients are included in the study of whom thirty patients were the study group and ten were taken as the control group. MDA levels of both groups and the differences between daily MDA levels of each group are compared statistically by using one way ANOVA, student t test and student Newman Keuls test respectively.
Results:
There was statistical significant difference between study and control group (p < 0.05). Also there was significant difference between MDA levels of infected, non-infected and control groups (p < 0.01). It was understood that high MDA levels in the study group source from infected group and there was no significant difference between non-infected and control group.
Conclusions:
In this study we proved the high MDA levels in the peritoneal fluid of Infected Acute Abdomen patients. This result is meaningful for the diagnose and following of these patients.
