[Role of the skin in destabilization of coronary circulation]

Our objective in this paper was to study diagnostic specificities of the skin secretion lipids fattyacid composition (FAC) in the precardiac region of patients with ischemic heart disease (IHD). Overall ninety two IHD patients who ranged from 34 to 78 years were examined together with fifteen clinically healthy persons. Used in the study were the gas-liquid chromatography techniques. The secured results suggested to us changes in the precardiac region skin lipids FAC in IHD. During the stage of compensation of coronary circulation the secretion of palmitic and docozohexaenic acids was found to have gotten diminished while that of saturated acids was augmented. This suggests to us a positive role of the skin, its negative role being in an increased secretion of monounsaturated fatty acids (MUFA), decreased secretion of representatives of omega-6 polyunsaturated fatty acids (PUFA). During the stage of decompensation the skin has predominantly a negative part (increased secretion of MUFA, docozohexaenic acids, decreased secretion of omega-6PUFA).