Related Experiment Video
Updated: Aug 11, 2026

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
Published on: November 28, 2015
Initial experience with dexmedetomidine in paediatric-aged patients
Joseph D Tobias1, John W Berkenbosch
1Department of Child Health, The University of Missouri, Columbia, Missouri 65212, USA. tobiasj@health.missouri.edu
Abstract:
We present preliminary clinical experience with the use of dexmedetomidine, an alpha2 adrenergic agonist, in children. Dexmedetomidine was administered in three clinical scenarios: (i) to provide sedation during mechanical ventilation; (ii) intraoperatively for controlled hypotension during an orthopaedic surgical procedure; and (iii) to provide sedation during an invasive procedure. Preliminary data from studies in the adult population, its physiological effects and potential applications in paediatric anaesthesia and critical care are discussed.
Related Concept Videos
Stages of General Anesthesia
Parenteral Anesthetics: Overview
Inhalational Anesthetics: Overview

