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[Rectal administration of misoprostol for delivery induced hemorrhage. Preliminary study]
R Shojai1, L Piéchon, C d'Ercole
1Service de Gynécologie Obstétrique (Pr L. Boubli), CHU Nord, 15, chemin des Bourrelys, 13015 Marseille. rahashojai@yahoo.com
Objective:
Assess the efficacy of one misoprostol tablet (Cytotec) in severe delivery-induced hemorrhage on uterine atony after failure of syntocinon.
Patients And Methods:
A descriptive study was conducted at the Djibouti Army Hospital from September to December 2000. Five patients with severe delivery-induced hemorrhage due to uterine atony unresponsive to syntocinon were give a tablet of misoprostol by rectal administration.
Results:
The hemorrhage ceased in less than 5 minutes in all patients. No immediate side effect was observed.
Discussion:
These preliminary findings are encouraging and suggest that further investigations would be useful to assess the beneficial effect of misoprostol by rectal administration for patients with severe delivery-induced hemorrhage due to uterine atony. Case-control studies with a sufficient number of cases should be undertaken to determine the real efficacy of misoprostol in this indication.