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Updated: Aug 15, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
The radiologic spectrum of pulmonary Aspergillus infections
Michael B Gotway1, Samuel K Dawn, Elaine M Caoili
1Department of Radiology, San Francisco General Hospital, San Francisco, CA 94110, USA. michael.gotway@radiology.ucsf.edu
Abstract:
Aspergillus infections may be categorized by specific radiographic patterns, the patient's immunologic status, and the presence or absence of preexisting structural lung disease. General patterns include invasive aspergillosis (both vascular and airway invasive varieties and acute tracheobronchitis), semiinvasive aspergillosis (including allergic bronchopulmonary aspergillosis and hypersensitivity pneumonitis), mycetoma, allergic aspergillosis, and obstructing bronchial aspergillosis. Knowledge of these various radiographic patterns as well as the immune derangements that accompany these infections may allow proper diagnosis.
Insights
This study categorizes Aspergillus infections using radiographic patterns and patient immunity. Understanding these classifications aids in accurate diagnosis of various fungal lung diseases.
Area of Science:
- Medical Mycology
- Pulmonary Medicine
- Radiology
Background:
- Aspergillus infections present diverse clinical and radiographic manifestations.
- Patient immunologic status and pre-existing lung conditions are critical factors in disease presentation.
- Accurate diagnosis relies on integrating imaging findings with host factors.
Purpose of the Study:
- To outline the classification of Aspergillus infections based on radiographic patterns.
- To correlate these patterns with patient immunologic status and structural lung disease.
- To emphasize the importance of recognizing these patterns for proper diagnosis.
Main Methods:
- Review of established classification systems for pulmonary Aspergillus infections.
- Correlation of radiographic findings with clinical and immunological data.
- Categorization based on invasive, semi-invasive, mycetoma, and allergic forms.
Main Results:
- Invasive aspergillosis includes vascular, airway, and tracheobronchitis patterns.
- Semi-invasive forms encompass allergic bronchopulmonary aspergillosis and hypersensitivity pneumonitis.
- Mycetoma and obstructing bronchial aspergillosis represent distinct entities.
Conclusions:
- Radiographic patterns are key to classifying Aspergillus lung infections.
- Integrating imaging with immune status improves diagnostic accuracy.
- Knowledge of these classifications is essential for effective patient management.
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