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Low-dose propofol infusion for sedation during local anesthesia
Hee-Dong Yoon1, Eul-Sik Yoon, Eun-Sang Dhong
1Department of Anesthesiology, College of Medicine, Korea University Ansan Hospital, 516 Gogan-Dong, Ansan-City, Kyong gi-Do, 425-020 Republic of Korea.
Plastic and Reconstructive Surgery
|March 9, 2002
Summary
Low-dose propofol infusion provides safe and effective sedation for patients undergoing local anesthesia. This technique improved patient and surgeon satisfaction without increasing side effects or discharge time.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Sedation is crucial for patient comfort during local anesthesia.
- Optimizing sedative techniques can enhance procedural outcomes and patient experience.
Purpose of the Study:
- To evaluate the safety and efficacy of low-dose propofol infusion for sedation in patients undergoing surgery with local anesthesia.
- To compare propofol sedation with a placebo in terms of sedation level, hemodynamics, oxygen saturation, side effects, and patient/surgeon satisfaction.
Main Methods:
- A randomized controlled trial involving 90 patients undergoing local anesthesia.
- Patients received midazolam premedication followed by either low-dose propofol infusion or saline placebo.
- Key outcomes included sedation level, hemodynamic variables, oxygen saturation, adverse events, discharge time, and satisfaction.
Main Results:
- Propofol infusion effectively reduced patient discomfort and intraoperative hemodynamic parameters.
- Adequate sedation was achieved without significant oxygen desaturation.
- Higher satisfaction rates were reported by both patients and surgeons in the propofol group.
- No significant differences in adverse effects or discharge time were observed between groups.
Conclusions:
- Low-dose propofol infusion is a safe and effective sedative method for procedures utilizing local anesthesia.
- This technique enhances patient and surgeon satisfaction, making it a valuable option for procedural sedation.