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[New concepts in the biology of acute myeloid leukemia]

Juan José Montesinos1, Héctor Mayani

  • 1Unidad de Investigación en Enfermedades Oncológicas, Centro Médico Nacional Siglo XXI, IMSS. Av. Cuauhtémoc 330, Col. Doctores México, D.F. 06720.

Gaceta Medica De Mexico
|March 12, 2002
PubMed

During the last 20 years, several concepts regarding the biology of acute myeloid leukemia (AML) have changed in a profound manner. This has been mainly due to significant advances in the identification, purification and characterization of the primitive hematopoietic cells--including stem and progenitor cells--in which this disorder originates. In the present review article, we discuss some of these new concepts and their relevance in the treatment of AML.

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