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Terminal sedation for existential distress.

T Morita1, J Tsunoda, S Inoue

  • 1Seirei Mikatabara Hospital, Hamamatsu, Shizuoka, Japan.

The American Journal of Hospice & Palliative Care
|March 12, 2002
PubMed
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Improved accuracy of physicians' survival prediction for terminally ill cancer patients using the Palliative Prognostic Index.

Palliative medicine·2001

Sedation for existential distress in terminally ill cancer patients is rarely used alone. Empirical reports show palliative sedation primarily addresses physical symptoms like dyspnea and delirium in late-stage cancer.

Area of Science:

  • Palliative Care
  • Oncology
  • Medical Ethics

Background:

  • Existential distress is a significant concern for terminally ill cancer patients.
  • Empirical data on sedation for existential distress in palliative care is limited.
  • This study investigates the physical conditions of cancer patients receiving sedation for existential distress.

Observation:

  • 20 out of 248 hospice inpatients received sedation for existential distress.
  • Primary indications for sedation were dyspnea (10 patients), agitated delirium (8 patients), and pain (1 patient).
  • Only one patient received sedation solely for psychological distress; physical symptoms were often present and significant.

Findings:

  • Patients receiving sedation had severely diminished physical function (Palliative Performance Scale 10-20).

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  • Most patients had difficulty with oral intake and presented with edema, dyspnea at rest, and delirium.
  • High Palliative Prognostic Index scores (mean 12) indicated a very late stage of illness.
  • Implications:

    • In this practice, palliative sedation was predominantly used for managing severe physical symptoms in end-stage cancer patients.
    • Further research is needed to develop standardized therapies for existential distress in the terminally ill.
    • This study highlights the complex interplay of physical and psychological symptoms at the end of life.