Mitral valve replacement in ischemic mitral regurgitation. Preservation of both anterior and posterior mitral leaflets
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Updated: Oct 2, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
A Morishita1, T Shimakura, M Nonoyama
1Department of Cardiovascular Surgery, Fukuyama Cardiovascular Hospital, Fukuyama-shi, Hiroshima, Japan. atsumori@gol.com
Background:
The surgical risks associated with ischemic mitral regurgitation are thought to be greater than those for other forms of mitral regurgitation. We have performed mitral valve replacement using the St. Jude Medical bileaflet prostheses with preservation of both leaflets, along with all of the chordae tendineae and papillary muscles. The aim of this study was to retrospectively evaluate mitral valve replacement with preservation of both mitral valves with respect to long-term clinical results and left ventricular performance.
Methods:
Between January 1, 1988 and February 29, 2000, 15 patients were operated on for ischemic mitral regurgitation. There were 7 males and 8 females, and the mean age was 69.7+/-8.1 years. The preoperative variables showed clinical deterioration of the state, such as emergency operation in 40% of the patients, more than NYHA functional III class in 93% of patients, cardiogenic shock in 47% of the patients, a mean left ventricular ejection fraction of 36.8%, and a mean left ventricular end-systolic volume index of 116.7 ml/m2.
Results:
There were 5 (33.3%) hospital deaths during the follow-up period including 1 early death and 1 (10%) late death during the follow-up period. Thus, the actuarial survival rate after 5 years for the whole was 60%. However, the left ventricular dimensions and left ventricular fractional shortening, even if in patients with profound depressed left ventricular function preoperatively, showed maintenance of the cardiac function.
Conclusions:
These results suggested that mitral valve replacement using the St. Jude Medical prostheses with preservation of both leaflets and all chordae tendineae and papillary muscles might be a procedure of choice for ischemic mitral regurgitation.
Insights
Mitral valve replacement preserving leaflets, chordae, and papillary muscles shows potential for ischemic mitral regurgitation. This technique maintained cardiac function despite preoperative left ventricular dysfunction.
Area of Science:
- Cardiovascular Surgery
- Cardiac Valve Repair and Replacement
- Heart Failure Management
Background:
- Ischemic mitral regurgitation (IMR) carries higher surgical risks compared to other forms.
- Traditional mitral valve surgery may involve more extensive resection, potentially impacting left ventricular function.
- Preservation of native mitral valve structures (leaflets, chordae tendineae, papillary muscles) is explored as a less invasive approach.
Purpose of the Study:
- To retrospectively evaluate the long-term clinical outcomes and left ventricular (LV) performance after mitral valve replacement (MVR) in IMR patients.
- To assess the efficacy of MVR using St. Jude Medical bileaflet prostheses with preservation of native mitral valve components.
Main Methods:
- A cohort of 15 patients with IMR underwent mitral valve replacement between 1988 and 2000.
- The surgical technique involved preserving both mitral valve leaflets, chordae tendineae, and papillary muscles.
- Preoperative assessment included evaluation of NYHA functional class, cardiogenic shock, LV ejection fraction, and LV end-systolic volume index.
Main Results:
- Hospital mortality was 33.3% (5/15), with 1 early and 1 late death during follow-up.
- The 5-year actuarial survival rate was 60%.
- Despite preoperative depressed LV function, the procedure demonstrated maintenance of cardiac function, evidenced by preserved LV dimensions and fractional shortening.
Conclusions:
- Mitral valve replacement with preservation of leaflets, chordae tendineae, and papillary muscles may be a suitable option for IMR.
- This approach appears to maintain or improve left ventricular performance even in severely compromised patients.
- Further investigation into this technique for IMR is warranted.
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