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Updated: Jul 30, 2026

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Murine Model of Wound Healing
Published on: May 28, 2013
How to prepare the wound bed
1Johns Hopkins University School of Nursing, Baltimore, Md., USA. dlkrasner@aol.com
Ostomy/Wound Management
|March 14, 2002
Abstract:
This clinically focused article addresses the nuts and bolts of wound bed preparation. Preparing the wound bed is a frequently ignored step in the process of treating chronic wounds. In these days of high-tech instrumentation use for chronic wound care (i.e., adjunctive therapies, growth factors, and skin substitutes), clinicians should not forget the basics that are essential for optimizing wound healing. This article introduces the PREPARE Model (see Figure 1) as an aid for guiding care providers in wound bed preparation.

