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Updated: Jul 28, 2026

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Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
Published on: December 18, 2019
Col2-GFP reporter mouse--a new tool to study skeletal development
J Y Cho1, T D Grant, G P Lunstrum
1Research Center, Shriners Hospital for Children, Portland, OR 97201, USA.
American Journal of Medical Genetics
|March 14, 2002
Abstract:
Transgenic mice were generated that harbor a Col2-GFP reporter that marks chondrocytes and their immediate precursors during skeletal development. Cells engaged in chondrogenesis were identified by conventional fluorescence microscopy and confocal optical sectioning within their native environments in live embryos and in thick tissue slices. The use of these mice offers a novel approach for studying the role of chondrocytes in skeletal development.

