Related Experiment Video
Updated: Jul 24, 2026
08:05
Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Sinusitis and asthma: associated airway diseases.
1Northwest Asthma & Allergy Center, University of Washington, 4540 Sand Point Way NE, Seattle, WA 98105, USA. fvirant@nwasthma.com
Current Allergy and Asthma Reports
|March 15, 2002
Summary
Sinusitis often co-occurs with asthma, sharing similar tissue characteristics. Treating sinus issues can significantly improve asthma symptoms, indicating sinusitis may worsen asthma control.
Area of Science:
- Otolaryngology
- Pulmonology
- Allergy and Immunology
Background:
- Sinusitis and asthma are common airway diseases that frequently coexist in patients.
- Histological similarities exist between sinusitis and asthma, including tissue eosinophils, increased glandular tissue, and edema.
- Therapeutic interventions for sinusitis often lead to substantial improvements in asthma control.
Purpose of the Study:
- To explore the relationship between sinusitis and asthma exacerbation.
- To identify potential mechanisms linking sinus disease to worsened asthma.
- To emphasize the importance of considering sinusitis in the differential diagnosis of asthma triggers.
Main Methods:
- This study is a review of existing literature and clinical observations.
- It examines the histological similarities between the two conditions.
- It discusses proposed pathophysiological mechanisms connecting sinusitis and asthma.
Main Results:
- Sinusitis and asthma share common inflammatory pathways and histological features.
- Effective treatment of sinusitis frequently results in improved asthma symptoms and control.
- Proposed mechanisms include neural reflex pathways and impaired nasal physiological functions.
Conclusions:
- Sinusitis is a significant factor that can exacerbate asthma.
- Healthcare providers should evaluate patients with asthma for concurrent sinusitis.
- Addressing sinusitis may be a crucial component in managing difficult-to-control asthma.
Related Concept Videos
01:20Asthma: Pathogenesis and Management
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
01:29Asthma-I: Introduction
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
01:26Asthma-II: Pathophysiology and Classification
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
01:24Asthma-III: Symptoms and Complications
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
01:28Asthma I: Introduction
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
01:13Asthma III: Clinical Manifestations
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...