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Related Experiment Videos

[Tissue Doppler echocardiography: a new technique to assess diastolic function].

Mária Lengyel1, András Nagy, Agnes Zorándi

  • 1Gottsegen György Országos Kardiológiai Intézet, Budapest.

Orvosi Hetilap
|March 15, 2002
PubMed
Summary

Pulsed tissue Doppler echocardiography (PTDI) easily measures diastolic function, revealing associations between diastolic and systolic dysfunction. Decreased early diastolic tissue velocity indicates diastolic dysfunction, regardless of type or age.

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Area of Science:

  • Cardiology
  • Echocardiography
  • Heart Failure Research

Background:

  • Diastolic dysfunction and elevated filling pressures are critical in heart failure.
  • Traditional Doppler echocardiography (DE) has limitations in measuring these variables.
  • Pulsed tissue Doppler echocardiography of the lateral mitral annulus (PTDI) is a novel technique.

Purpose of the Study:

  • To evaluate the efficacy of PTDI in assessing diastolic function.
  • To compare PTDI with traditional DE for measuring diastolic parameters.
  • To investigate the relationship between diastolic dysfunction and systolic function using PTDI.

Main Methods:

  • 96 patients in sinus rhythm without mitral valve disease were studied.
  • Ejection fraction was either >= 50% or <= 40%.

Related Experiment Videos

  • DE measured mitral E, A velocities, and deceleration time; PTDI measured myocardial early diastolic (Ea) and late diastolic (Aa) velocities at the lateral mitral annulus.
  • Main Results:

    • PTDI revealed an association between diastolic and systolic dysfunction, not evident with DE.
    • Myocardial Ea velocity < 15 cm/s indicated diastolic dysfunction across all types.
    • An E/Ea ratio > 8 suggested elevated filling pressure, correlating with E/A ratio only in preserved systolic function.

    Conclusions:

    • PTDI allows easy measurement of myocardial diastolic velocities.
    • Decreased early diastolic tissue velocity signifies diastolic dysfunction, irrespective of type or age.
    • Pseudonormalization is characterized by normal mitral inflow and reduced tissue diastolic velocity.