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Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
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Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

AMOP, a protein module alternatively spliced in cancer cells

Francesca D Ciccarelli, Tobias Doerks, Peer Bork

    Trends in Biochemical Sciences
    |March 15, 2002
    PubMed
    Summary

    Researchers identified a novel protein domain, the adhesion-associated domain (AMOP), crucial for cell adhesion. This domain is found in MUC4 splice variants, which are overexpressed in pancreatic tumors, suggesting a role in cancer progression.

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