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[Detection of adenovirus type-12 in sarcomas induced by this virus in hamster]
Voprosy Onkologii
|January 1, 1975
Abstract:
Cells of transplantable sarcomas primarily induced in hamsters with adenovirus, type 12, produced persistantly this virus in an infective form. In sera of sarcomabearing hamsters virus-neutrolizing antibodies and antibodies to T-antigen of tumors were revealed. The presence of T-antigen in cells of all types of sarcoma A-12 was demonstrated by means of immunofluorescence, as well as the absence of a specific luminescence of surface membranes of A-12 MML sarcoma cells, obtained from pulmonary micrometastases.