A study on gender and age differences in sleep spindles
Related Experiment Video
Updated: Oct 2, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
Published on: August 2, 2017
Eero Huupponen1, Sari-Leena Himanen, Alpo Värri
1Digital and Computer Systems Laboratory, Tampere University of Technology, Finland. eeroh@cs.tut.fi
Abstract:
In the present work, gender differences in sleep spindle topography were examined in 40 subjects. Their median age was 32 years (range 22-49 years). Spindles were detected from 3,306,060 s of visually scored stage 2 sleep EEG by a previously validated automatic fuzzy detector at 1-second intervals. A total of 271,168 spindles were found from the six EEG channels analyzed. Females showed a significantly higher percentage of spindles in the left frontal channel than males (Fp1-A2; p = 0.026). To confirm that this difference was gender and not age related, the subjects were divided into two age groups. No significant differences in spindle activity of the frontal channels were found between the groups. However, the interindividual spindle variability seemed to be at least as large as that stemming from gender.

