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Nucleotides as semiessential nutritional components
1Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Granada, Spain. sanchezp@platon.ugr.es
The British Journal of Nutrition
|March 16, 2002
Abstract:
Dietary nucleotides are required nutrients for some tissues under certain circumstances. A lack of dietary nucleotides negatively influences protein synthesis in both the liver and the small intestine of rats. Ribosome degradation has been observed as being among the mechanisms responsible for this effect. Dietary nucleotides can also modulate gene expression by interaction with specific transcription factors, in both the liver and the small intestine.