[Differential diagnosis and follow-up studies in sucklings and infants with continuous cholestasis (author's transl)]

Among liver biopsies from 91 children between the age of 36 hrs and 2 years, puncture or excision was done for clarification in 64 cases. The morphological differential diagnosis between the various forms of intra- and extrahepatic bile duct dysplasias and their define characteristics related to hepatitis is presented. Morphological changes have given the basis for our grouping of diseases with cholestasis in early childhood. Our conclusions were summarized and proved in some schematic tables. Particular emphasis was given to comparative time observations for bioptic examined children over longer periods. Hereby results prognostic knowledge which should stimulate our therapeutic handling.