Related Experiment Video
Updated: Aug 14, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Adult-onset facial colloid milium successfully treated with the long-pulsed Er:YAG laser
Christie T Ammirati1, Joseph M Giancola, George J Hruza
1Division of Dermatology, Penn State College of Medicine, Milton Hershey Medical Center, Hershey, Pennsylvania 17033, USA. cammirati@psu.edu
Background:
Adult colloid milium is a rare cutaneous deposition disorder that frequently involves areas of chronic sun exposure, especially the face and dorsal hands. Attempts to remove these lesions are generally unsuccessful, but dermabrasion has been reported to be effective.
Objective:
To present an effective therapeutic alternative to dermabrasion for facial colloid milium.
Methods:
A 41-year-old man with extensive facial colloid milium underwent full-face resurfacing with a long-pulsed Er:YAG laser (9.8 J/cm2, 5 mm spot, 10-msec pulse duration). Additional passes were performed over the areas of dense colloid milium to achieve approximately 80% ablation of lesions.results. At the 7-month follow-up there was no scarring, textural changes, dyspigmentation, or clinical evidence of recurrence.
Conclusion:
Long-pulsed Er:YAG laser should be considered an effective alternative to dermabrasion for facial colloid milium.

