Related Experiment Video
Updated: Feb 25, 2026
06:59
Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
636
Lung cavitation in primary antiphospholipid syndrome
A M Bertoli1, A H Tabares, J P Casas
1Rheumatology Department, Hospital Privado, Centro Médico de Córdoba, Argentina.
Lupus
|March 20, 2002
Summary
Primary antiphospholipid syndrome frequently causes diverse pulmonary complications, most commonly thromboembolic events. This case highlights a patient experiencing pulmonary thromboembolism, infarction, and subsequent lung cavitation due to primary antiphospholipid syndrome.
Area of Science:
- Pulmonology
- Rheumatology
- Pathology
Background:
- Primary antiphospholipid syndrome (PAPS) is an autoimmune disorder characterized by recurrent thrombosis and pregnancy morbidity.
- Pulmonary manifestations are recognized complications of PAPS, often presenting as thromboembolic disease.
Observation:
- A female patient with diagnosed primary antiphospholipid syndrome presented with significant pulmonary complications.
- The patient experienced a pulmonary thromboembolic event and subsequent pulmonary infarction.
Findings:
- The pulmonary infarction progressed, leading to the development of lung cavitation.
- This case illustrates a rare but severe pulmonary sequela of primary antiphospholipid syndrome.
Implications:
- This case underscores the importance of recognizing diverse pulmonary manifestations in primary antiphospholipid syndrome.
- Early diagnosis and management of pulmonary complications in PAPS are crucial to prevent severe outcomes like lung cavitation.
More Related Videos
Related Concept Videos
01:30Peripheral Artery Disease I: Introduction
451
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
451
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
533
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
533
01:29Pulmonary Embolism I: Introduction
942
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
942
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
370
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
370
01:30Venous Thrombosis I: Introduction
535
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
535
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
507
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
507