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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

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Related Experiment Video

Updated: Jul 22, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

Immunotherapy for food allergy.

L G Wild1, S B Lehrer

  • 1Department of Medicine, Section of Clinical Immunology, Allergy and Rheumatology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA. lwild@tulane.edu

Current Allergy Reports
|March 20, 2002
PubMed
Summary

Food allergy immunotherapy is developing new treatments to prevent and manage life-threatening reactions. Research explores options like peptide immunotherapy and DNA immunization for effective food allergy prevention.

Area of Science:

  • Immunology
  • Allergy Research
  • Hypersensitivity Reactions

Background:

  • Food allergy causes severe hypersensitivity reactions, necessitating strict allergen avoidance.
  • Current avoidance strategies are challenging and often impractical for patients.
  • Understanding immunologic mechanisms is key to developing new interventions.

Purpose of the Study:

  • To review emerging therapeutic modalities for food allergy treatment and prevention.
  • To highlight novel approaches beyond allergen avoidance.

Main Methods:

  • Investigational therapies include peptide immunotherapy, DNA immunization, and immunostimulatory sequences.
  • Other approaches involve anti-IgE therapy and genetic modification of foods.
  • These methods are based on improved allergen characterization and immunologic understanding.

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Last Updated: Jul 22, 2026

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

Basophil Activation Test for Allergy Diagnosis
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Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Main Results:

  • Several therapeutic options show promise for managing food allergies.
  • These treatments aim to provide safe and effective alternatives to avoidance.

Conclusions:

  • New therapeutic strategies offer hope for the future treatment and prevention of food allergies.
  • Advancements in immunotherapy and genetic approaches are expected in the coming years.