Intraocular teratoma in a mouse
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Updated: Oct 2, 2026

05:46
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Richard S Smith1, James V Miller, John P Sundberg
1The Jackson Laboratory, Bar Harbor, Maine, USA.
Comparative Medicine
|March 20, 2002
Abstract:
A 4.5-month-old male B6.129S2-Trp53tm1Tyj mouse developed an enlarged left eye. After euthanasia, the eye was removed and found to contain a teratoma composed of smooth muscle, white fat, neural tissue, and villous intestinal epithelium with appearance similar to that of the small intestine. Many normal intraocular structures were absent. To our knowledge, this represents the first reported intraocular teratoma in a mouse.

