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Related Experiment Videos

Persistent fifth aortic arch in man.

T Y Lawrence, Q R Stiles

    American Journal of Diseases of Children (1960)
    |October 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    This study reports a rare fifth aortic arch vascular anomaly without intracardiac defects, unique due to patient survival and prenatal trimethadione exposure. The patient

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    Area of Science:

    • Cardiovascular Medicine
    • Developmental Biology
    • Teratology

    Background:

    • Persistence of the fifth aortic arch is a rare congenital vascular anomaly.
    • Typically associated with intracardiac malformations and patent ductus arteriosus.
    • Previous cases have not reported survival or prenatal drug exposure.

    Observation:

    • A unique case of fifth aortic arch persistence is presented.
    • The patient survived despite the anomaly and had no intracardiac malformations.
    • Prenatal exposure to the anticonvulsant trimethadione (Tridione) was noted.

    Findings:

    • The fifth aortic arch anomaly persisted without associated intracardiac malformations.
    • The patient survived with this rare vascular anomaly.

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  • Congenital defects including hip dislocation and patent ductus arteriosus were present.
  • Implications:

    • This case expands the understanding of fifth aortic arch persistence.
    • Highlights the potential for survival in rare vascular anomalies.
    • Suggests a possible link between prenatal trimethadione exposure and congenital defects.