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Related Experiment Videos

Self-oscillating polymer chain in a laser field.

H Mayama1, K Yoshikawa

  • 1Department of Physics, Graduate School of Science, Kyoto University, CREST (Core Research for Evolutional and Scientific Technology) of JST (Japan Science and Technology Corporation), Kyoto 606-8502, Japan. mayama@chem.scphys.kyoto-u.ac.jp

Faraday Discussions
|March 21, 2002
PubMed
Summary

Researchers observed rhythmic conformational changes in a single polymer chain using a focused laser. This study clarifies the melting, nucleation, and growth processes involved in these polymer dynamics.

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Area of Science:

  • Polymer Physics
  • Biophysics
  • Laser Physics

Background:

  • Single polymer chains exhibit complex conformational dynamics.
  • Understanding these dynamics is crucial for various applications, including nanotechnology and molecular biology.
  • Thermodynamically open systems offer unique environments for studying such phenomena.

Purpose of the Study:

  • To investigate the rhythmic conformational changes between folded and unfolded states in a single polymer chain.
  • To elucidate the mechanism driving these conformational transitions under open conditions.
  • To analyze the role of laser-induced temperature gradients in polymer dynamics.

Main Methods:

  • Utilizing a focused continuous wave (CW) Nd:YAG laser beam (1064 nm) to trap and manipulate a single T4DNA polymer chain (166 kbp).

Related Experiment Videos

  • Employing laser-induced temperature gradients to drive conformational changes.
  • Observing and analyzing the dynamics of melting, nucleation, and growth processes.

    • Main Results:

    • Demonstrated the generation of spontaneous rhythmic conformational changes in a single polymer chain.
    • Clarified the step-by-step process of melting, nucleation, and growth during conformational transitions.
    • Identified the dual role of the focused laser in trapping the polymer and creating a temperature gradient.

    Conclusions:

    • The observed rhythmic conformational change is a limit-cycle oscillation.
    • Photon energy dissipation from the laser drives these oscillations.
    • This study provides insights into the controlled manipulation of polymer conformations.