Related Experiment Video
Updated: Oct 2, 2026

Whole-cell MALDI-TOF Mass Spectrometry is an Accurate and Rapid Method to Analyze Different Modes of Macrophage Activation
Published on: December 26, 2013
MALDI TOF mass spectrometry: an emerging platform for genomics and diagnostics
1Sequenom, Inc., 3595 John Hopkins Court, San Diego, CA 92121, USA. jleushner@sequenom.com
Abstract:
Matrix-assisted laser desorption/ionization-time of flight (MALDI TOF) mass spectrometry has become, in recent years, a tool of choice for large molecule analyses. The platform is ideal for analysis of protein and nucleic acid sequence, structure and purity. MALDI TOF is the method of choice for quality assurance in oligo and peptide synthesis. Exact mass measurements along with signal intensity detection provide a high level of quality assurance as to the accuracy of the measurement. This accuracy has the potential to significantly lower the level of indeterminate assays that require retest.
Related Concept Videos
MALDI-TOF Mass Spectrometry
Rapid Identification of Pathogens
Tandem Mass Spectrometry
Peptide Identification Using Tandem Mass Spectrometry
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
Matrix-Assisted Laser Desorption Ionization (MALDI)
Mass Spectrometry: Complex Analysis
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...

