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Association mapping: where we've been, where we're going
1North Carolina State University, Program in Statistical Genetics, Department of Statistics, Raleigh, NC 27695-7566, USA. dahlia@statgen.ncsu.edu
Expert Review of Molecular Diagnostics
|March 21, 2002
Abstract:
This paper provides a review of recent work in the area of marker-phenotype association studies, specifically as used for localizing--or mapping--genes affecting a trait of interest. We describe the basis of association mapping and discuss a number of the commonly used techniques. We have also included references to various papers that have evaluated the use of these methods.