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Metastatic disease involving the stomach
The American Journal of Digestive Diseases
|October 1, 1975
Summary
Gastric metastases are uncommon but challenging. This autopsy review found 1.7% of cancer patients had stomach metastases, most frequently from breast, lung, or melanoma. Radiography aids diagnosis of these nonspecific symptoms.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Metastatic disease to the stomach is rare and clinically challenging.
- Gastric metastases represent a small fraction of secondary cancer spread.
- Identifying the primary tumor source is crucial for patient management.
Purpose of the Study:
- To determine the incidence and primary sources of gastric metastases.
- To evaluate the clinical and radiographic presentation of gastric metastases.
Main Methods:
- Retrospective review of 1010 autopsy cases.
- Analysis of cancer patient records to identify gastric involvement.
- Correlation of primary cancer types with gastric metastasis occurrence.
Main Results:
- Gastric metastases were found in 1.7% of autopsied cancer patients (17 out of 1010).
- Most frequent primary cancers leading to gastric metastases were breast cancer, lung cancer, and melanoma.
- Common clinical symptoms include epigastric pain, melena, and anemia, which are nonspecific.
Conclusions:
- Gastric metastases are an infrequent finding in cancer autopsies.
- Breast, lung, and melanoma are the most common origins of gastric metastases.
- Radiographic examination is essential for diagnosing gastric metastases due to nonspecific clinical signs.