Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ki67 protein: the immaculate deception?

D C Brown1, K C Gatter

  • 1Department of Histopathology, Whittington Hospital, London, UK.

Histopathology
|March 21, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing outcome measure development and analytical approaches: Pain in Animals Workshop 2023.

Frontiers in pain research (Lausanne, Switzerland)·2025
Same author

Outcome assessment in veterinary pain studies: a pain in animals workshop (PAW) perspective.

Frontiers in pain research (Lausanne, Switzerland)·2025
Same author

Biochemical Genetics of Fundulus heteroclitus (L.): V. Inheritance of 10 Biochemical Loci.

The Journal of heredity·2019
Same author

Measurement of chronic pain in companion animals: Priorities for future research and development based on discussions from the Pain in Animals Workshop (PAW) 2017.

Veterinary journal (London, England : 1997)·2019
Same author

Measurement of chronic pain in companion animals: Discussions from the Pain in Animals Workshop (PAW) 2017.

Veterinary journal (London, England : 1997)·2019
Same author

Spontaneous painful disease in companion animals can facilitate the development of chronic pain therapies for humans.

Osteoarthritis and cartilage·2017
Same journal

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma.

Histopathology·2026
Same journal

Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges.

Histopathology·2026
Same journal

A CRX-positive RB1-deficient bone tumour with a retinoblastoma-like DNA methylation profile.

Histopathology·2026
Same journal

Perivascular epithelioid cell tumours of the genitourinary tract: clinicopathological features and molecular landscape.

Histopathology·2026
Same journal

Navigating diagnostic challenges in low-grade spindle cell lesions of the breast: a retrospective review.

Histopathology·2026
Same journal

Neoplastic transformation of sporadic gastric hyperplastic polyps: a systematic review and meta-analysis of risk factors and clinicopathological features.

Histopathology·2026
See all related articles

This review updates knowledge on the Ki67 protein, a key marker in cell proliferation. Research on Ki67 has surged, highlighting its diagnostic and prognostic importance in various diseases.

Area of Science:

  • Immunohistochemistry
  • Cell Biology
  • Cancer Research

Background:

  • The Ki67 antibody is a widely used marker for cell proliferation.
  • Previous reviews have established its significance, but advancements necessitate updates.
  • There has been a tenfold increase in publications related to Ki67 in the last decade.

Purpose of the Study:

  • To provide an updated review of the Ki67 protein.
  • To discuss the characterization and function of Ki67.
  • To evaluate the evolving role of Ki67 as a diagnostic and prognostic tool.

Main Methods:

  • Literature review and synthesis of recent studies on Ki67.
  • Analysis of trends in Ki67 research publications.
  • Evaluation of Ki67's application in clinical pathology.

Related Experiment Videos

Main Results:

  • Ki67 research has expanded significantly, with a tenfold increase in published papers.
  • The Ki67 protein's characterization and functional roles continue to be elucidated.
  • Ki67 remains a critical tool for assessing cell proliferation in diagnostic and prognostic settings.

Conclusions:

  • The Ki67 antibody is a vital marker with increasing research interest.
  • Continued research is refining our understanding of Ki67's utility in disease management.
  • This review consolidates current knowledge on Ki67 for researchers and clinicians.