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Methotrexate treatment for refractory subacute cutaneous lupus erythematosus
Annegret Kuhn1, Christof Specker, Thomas Ruzicka
1Department of Dermatology, Heinrich-Heine-University, Düsseldorf, Germany.
Journal of the American Academy of Dermatology
|March 22, 2002
Abstract:
Methotrexate is beneficial in rheumatoid arthritis and has been used in small studies of patients with systemic lupus erythematosus. We describe a patient with severe subacute cutaneous lupus erythematosus refractory to therapy with antimalarials and corticosteroids. Treatment with methotrexate resulted in complete clearing of the skin lesions without any side effects.