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Neogrifolin derivatives possessing anti-oxidative activity from the mushroom Albatrellus ovinus
Makiko Nukata1, Toshihiro Hashimoto, Isao Yamamoto
1Faculty of Food Culture, Kurashiki Sakuyo University, 710-0290, Kurashiki, Japan.
Abstract:
Three neogrifolin derivatives, 3-hydroxyneogrifolin, 1-formylneogrifolin and 1-formyl-3-hydroxyneogrifolin along with grifolin and neogrifolin were isolated from the Japanese mushroom Albatrellus ovinus belonging to Scutigeraceae. Their structures were established by a combination of two-dimensional NMR spectroscopic analyses and by chemical synthesis. 3-Hydroxyneogrifolin and 1-formyl-3-hydroxy-neogrifolin showed more potent antioxidative activity properties than either alpha-tocopherol or BHA.
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