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[Pregnancy and AIDS. Report of 9 cases]
A Chakib1, M Laghzaoui Boukaidi, J Najib
1Service des maladies infectieuses, CHU Ibn-Rochd Casablanca.
La Tunisie Medicale
|March 26, 2002
Summary
HIV-positive mothers pose a transmission risk to their infants. This study on 9 deliveries found 2 newborns were infected despite antiretroviral therapy and preventative measures, highlighting ongoing challenges in preventing mother-to-child HIV transmission.
Area of Science:
- Infectious Diseases
- Obstetrics & Gynecology
- Pediatrics
Context:
- Pregnancy in women infected with Human Immunodeficiency Virus (HIV) presents a significant risk of vertical transmission to the child.
- This retrospective study analyzed 9 deliveries from HIV-infected mothers over a decade (1990-1999) at Casablanca CHU Ibn-rochd.
Purpose:
- To evaluate the experience of managing HIV-infected pregnant women in Infectious Diseases and Maternity services.
- To identify a potential protocol for preventing mother-to-child HIV transmission.
Summary:
- Antiretroviral therapy (ART) was administered in 8 out of 9 cases, with 6 receiving a long AZT protocol and 2 receiving bitherapy.
- All deliveries occurred vaginally with intrapartum AZT prophylaxis. All infants received postnatal AZT syrup, and breastfeeding was avoided.
- Despite these interventions, 2 out of 9 newborns were infected with HIV.
Impact:
- The findings underscore the persistent challenge of preventing mother-to-child HIV transmission even with established prophylactic measures.
- Highlights the need for refined strategies and continued vigilance in managing HIV-positive pregnancies to improve infant outcomes.