[Is the limitation to 6 cycles of insemination with donor sperm justified?]
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The Immediate Partial Removal of Cumulus-Oocyte Complexes: A Refined Approach for Rapid Observation of In Vitro Fertilization
Published on: October 18, 2024
1Unité de biologie de la reproduction, CECOS de l'Ouest, CHR Hôtel-Dieu, 1, bis rue de la Cochardière, 35000 Rennes, France. Dominique.Le-Lannou@univ-rennes1.fr
Objective:
To evaluate the effect of the limitation at 6 cycles of artificial insemination in a program of sperm donation.
Study Design:
266 couples included in a program of sperm donation underwent 1,354 cycles including 532 intracervical insemination (ICI), 678 intrauterine insemination (IUI) and 133 in vitro fertilization (IVF).
Results:
The birth rate by cycle was 10.8% in ICI, 18% in IUI, 21.9% in IVF. The risk of multiple pregnancies was 0% in ICI, 13% in IUI, 33% in IVF. The authors feign then two strategies, the first one with 6 ICI followed by 6 IUI, and the other one with 6 IUI alone. The birth rate, the risk of multiple pregnancies and the cost of these two strategies is discussed.
Conclusion:
The restriction to 6 IA Cycles in a donor semen program does not change the birth rate, but increases the multiple pregnancy rate and the cost of the treatment of these patients.
