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Natural transformation in Helicobacter pylori: DNA transport in an unexpected way
Leonard C Smeets1, Johannes G Kusters
1Dept of Medical Microbiology and Infection Control, VU University Medical Center, PO box 7057, 1007 MB, Amsterdam, The Netherlands. LC.Smeets@vumc.nl
Trends in Microbiology
|March 26, 2002
Abstract:
Like other bacterial species with a high frequency of inter-strain recombination, the human gastric pathogen Helicobacter pylori is competent for natural transformation. Recent data, however, indicate that its DNA-uptake system differs significantly from that in other species that contain DNA-uptake systems related to type IV pili. Instead, in H. pylori it has been suggested that the five proteins that form the transmembrane channel of the transformation system are closely related to subunits of type IV secretion systems.