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Type 2 diabetes therapy. A pathophysiologically based approach.
Adam B Mayerson1, Silvio E Inzucchi
1Yale University School of Medicine, 333 Cedar St, TMP 534, PO Box 208020, New Haven, CT 06520-8020, USA.
Postgraduate Medicine
|March 27, 2002
Summary
Physicians now have many oral antidiabetic agents to manage type 2 diabetes. Choosing the best medication involves considering glycemic control, mechanism of action, side effects, and nonglycemic benefits for individual patients.
Area of Science:
- Endocrinology
- Pharmacology
Background:
- Type 2 diabetes management has expanded with new oral antidiabetic agents.
- Physicians face a growing number of treatment options.
Purpose of the Study:
- To review the factors influencing the selection of oral antidiabetic agents.
- To highlight the importance of personalized treatment strategies.
Main Methods:
- Literature review of oral antidiabetic drug classes.
- Analysis of mechanisms of action, side effect profiles, and nonglycemic benefits.
Main Results:
- Glycemic control remains the primary objective in treatment selection.
- Individual patient factors, including side effects and nonglycemic benefits, are crucial.
Conclusions:
- Optimal selection of oral antidiabetic agents requires a comprehensive approach.
- Considering drug mechanisms, side effects, and patient-specific needs ensures effective type 2 diabetes management.