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Severe opiate withdrawal in a heroin user precipitated by a massive buprenorphine dose
Nicolas C Clark1, Nicholas Lintzeris, Peter J Muhleisen
1Turning Point Alcohol & Drug Centre, Fitzroy, VIC. nicoc@turningpoint.org.au
The Medical Journal of Australia
|March 27, 2002
Abstract:
By diverting his dispensed medication, our patient collected 11 buprenorphine tablets (8 mg each), which he took in one day. The result was not respiratory depression, but instead severe opiate withdrawal lasting four days--this scenario has not previously been reported. This case highlights features of the unique pharmacology of buprenorphine and some key issues for its use in the management of heroin dependence.