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Changes in left ventricular filling pattern during dobutamine stress Doppler echocardiography
1Cardiology Unit, Marina Baixa Hospital, Partida Galandú 5, 03570 La Vila Joiosa, Spain.
Summary
Stress Doppler echocardiography reveals that an increased E-wave deceleration time can detect myocardial ischemia. This analysis of left ventricular filling aids in identifying ischemia in patients.
Area of Science:
- Cardiology
- Diagnostic Imaging
- Echocardiography
Background:
- Myocardial ischemia detection is crucial for cardiovascular health.
- Doppler echocardiography offers insights into cardiac function.
- Left ventricular filling patterns can be altered by ischemic events.
Purpose of the Study:
- To investigate left ventricular filling patterns during stress Doppler echocardiography.
- To assess the utility of these patterns in detecting myocardial ischemia.
Main Methods:
- Fifty-seven patients underwent dobutamine stress echocardiography.
- Left ventricular filling parameters (E-wave velocity, A-wave velocity, E/A ratio, E-wave deceleration time) were analyzed at baseline and peak heart rate.
- Changes in these parameters were correlated with induced myocardial ischemia.
Main Results:
- E-wave deceleration time increased significantly in the ischemic group (P<0.0001) but decreased in the non-ischemic group (P=0.01).
- A >30% increase in E-wave deceleration time demonstrated high predictive values (93% positive, 86% negative) for ischemia.
- Increased E-wave deceleration time was the sole significant Doppler predictor of ischemia in multivariate analysis (P<0.0001).
Conclusions:
- Myocardial ischemia is associated with an increased E-wave deceleration time.
- Left ventricular filling analysis during stress echocardiography is valuable for identifying myocardial ischemia.