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Is transdifferentiation in trouble?

William A Wells¹

¹wellsw@rockfeller.edu

The Journal of Cell Biology

|March 28, 2002

Abstract:

Spectacular examples of transdifferentiation--such as brain cells turning to blood and blood to brain--have given way to sneaking suspicions about artifacts in culture, fusion, and clonality. Could cell fates be relatively fixed after all?

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