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Related Experiment Videos

Preseptal cellulitis caused by trichophyton (ringworm).

Andrew J Velazquez1, Michael H Goldstein, William T Driebe

  • 1University of Florida, College of Medicine, Department of Ophthalmology, Gainesville, FL 32601, USA.

Cornea
|March 28, 2002
PubMed
Summary
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A rare fungal infection caused preseptal cellulitis in a child, resistant to standard treatments. Oral itraconazole successfully treated the dermatophyte infection, highlighting a new therapeutic approach for this condition.

Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Preseptal cellulitis is a common eyelid infection, typically treated with antibiotics.
  • Fungal etiologies are rare but can present with similar symptoms, complicating diagnosis and treatment.

Observation:

  • A 10-year-old boy presented with a 15-day history of worsening right preseptal cellulitis, photophobia, pruritus, and pain.
  • Vesicular lesions were noted on the eyelids, and initial empiric antibacterial and antiviral therapy failed.

Findings:

  • Lid cultures identified coagulase-negative Staphylococcus, Streptococcal viridans, and a Trichophyton species of fungus.
  • The patient's preseptal cellulitis resolved after two courses of oral itraconazole, indicating successful treatment of the fungal infection.

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Implications:

  • This case represents the first reported instance of preseptal cellulitis caused by a dermatophyte fungus.
  • It underscores the importance of considering fungal pathogens in refractory preseptal cellulitis, especially with atypical presentations.
  • Successful treatment with itraconazole suggests its potential as a therapeutic option for similar rare fungal infections.