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Updated: Oct 2, 2026

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
Published on: March 6, 2018
[Occupational toxic exposure in the pregnant woman. 1: principles fo individual risk assessment ]
F Testud1, R Lambert-Chhum, B Bellemin
1Unité de Toxicovigilance, Centre Antipoison, Hôpital Edouard-Herriot, 69437 Lyon.
Context:
Many women of childbearing age are occupationally exposed to chemicals and concerned with the ensuing risk when pregnant.
Objectives:
To describe the principles of individual risk assessment to be applied in pregnant women or women wishing to become pregnant that are exposed to chemicals at the workplace.
Method:
Each request for risk assessment is based on a comprehensive review of the hazards of the handled products together with a thorough evaluation of the actual exposure at the workplace. A toxicological advice is then written to the gynecologist or the general practitioner in charge of the patient. When the exposure is estimated to be hazardous for the pregnancy, either total withdrawal, avoidance of certain activities or improvements of individual protective devices are recommended. The outcome of the pregnancy is systematically followed-up.
Conclusion:
An objective assessment of toxic risks in pregnant women exposed to chemicals at the workplace can be done. Thus, patients who must be withdrawn or benefit from improvements of their workstation can be selected.
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