Headache as a manifestation of fatal myocardial infarction
1Department of Internal Medicine, Division of Cardiology and Intensive Care, General Hospital Wels, Austria.
Insights
Headache can be the sole symptom of myocardial ischemia, a heart attack. This rare presentation, often due to nerve pathway convergence, makes diagnosis challenging and requires high clinical suspicion.
Area of Science:
- Cardiology
- Neurology
Background:
- Myocardial ischemia commonly presents as chest pain, but atypical symptoms can occur.
- The convergence of cardiac and somatic afferent pathways in the central nervous system may explain referred pain.
- Headache as an isolated symptom of cardiac ischemia is exceptionally rare.
Observation:
- A 47-year-old male presented with isolated occipital headache as the sole presenting symptom.
- Electrocardiography showed ST-segment elevation and depression, indicative of acute myocardial infarction.
- Ventricular fibrillation occurred during monitoring, leading to unsuccessful resuscitation.
Findings:
- Autopsy revealed severe coronary artery disease, including occlusion of the left anterior descending artery and significant stenosis of the right coronary artery.
- The patient's myocardial ischemia manifested exclusively as headache, with no typical chest pain.
- This case highlights the potential for neurological symptoms to be the primary manifestation of acute cardiac events.
Implications:
- Clinicians must maintain a high index of suspicion for myocardial ischemia in patients presenting with unexplained headaches, even in the absence of chest pain.
- Understanding the neuroanatomical basis of referred pain is crucial for diagnosing rare presentations of ischemic heart disease.
- This case underscores the importance of considering cardiac etiologies in emergency room presentations of severe headache.
Abstract:
Cardiac ischemia typically causes chest pain, variously radiating elsewhere. Convergence of cardiac nerve fibers on central pathways receiving somatic afferents from the head is likely to be responsible for the perception of cardiac ischemic pain as headache. A 47-year-old man was admitted to the emergency room of our hospital with a 2-hour history of occipital headache. Routine electrocardiography revealed monophasic ST-segment elevation in leads I and aVL and ST-segment depression in leads II, III, and aVF. During recording of lead VI, ventricular fibrillation occurred. Advanced life support was started immediately but failed to restore rhythm and cardiac function. Autopsy showed two-vessel disease with a ruptured plaque and total thrombotic occlusion of the proximal left anterior descending artery and 80% stenosis of the right coronary artery. In this patient, headache was the only symptom of myocardial ischemia. Anatomic convergence of cardiac nerve fibers on central pathways receiving somatic afferents from the head is likely to be responsible for the perception of cardiac ischemic pain as headache. Owing to the very rare occurrence of headache as a symptom of myocardial ischemia, diagnosis is difficult and requires a high degree of suspicion.
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