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A novel antibiotic CJ-17,572 from a fungus, Pezicula sp
Yutaka Sugie1, Koen A Dekker, Taisuke Inagaki
1Exploratory Medicinal Sciences, PGRD, Nagoya Laboratories, Pfizer Pharmaceuticals, Inc., Aichi, Japan. Yutaka.Sugie@japan.pfizer.com
The Journal of Antibiotics
|March 29, 2002
Abstract:
A new antibiotic, CJ-17,572 (I) was isolated from the fermentation broth of a fungus Pezicula sp. CL11877. The structure of I was determined to be a new equisetin derivative by spectroscopic analyses. The compound inhibits the growth of multi-drug resistant Staphylococcus aureus and Enterococcusfaecalis with IC50s of 10 and 20 microg/ml, respectively.