Unraveling heterochromatin

Protocol for CRISPR genome editing in S. cerevisiae using PCR-based guide insertion.

STAR protocols·2026

Tandem bromodomains of BRD4 cooperatively read poly-acetylated nucleosomes to enhance chromatin engagement and regulate breast cancer phenotypes.

bioRxiv : the preprint server for biology·2026

Discovery of Small-Molecule Antagonists of PHF1 and 19 Demonstrates the Ligandability of PRC2 Accessory Proteins.

ACS bio & med chem Au·2026

Rapid CRISPR-Cas9 Genome Editing in S. cerevisiae.

bioRxiv : the preprint server for biology·2026

Chromatin stability safeguards mitochondrial homeostasis and prevents mTORC1 hyperactivation.

bioRxiv : the preprint server for biology·2025

HMGN1 and HMGN2 are recruited to acetylated and histone variant H2A.Z-containing nucleosomes to regulate chromatin state and transcription.

The Journal of biological chemistry·2025

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

Nature genetics·2026

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Nature genetics·2026

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection.

Nature genetics·2026

hnRNPK condensates facilitate enhancer-promoter looping and RNA polymerase II recruitment.

Nature genetics·2026

Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer's disease.

Nature genetics·2026

Prevalence and chronology of colibactin-associated mutational processes and their microbiome spectra in Japanese colorectal cancer.

Nature genetics·2026

HIPK4 is a novel gene associated with teratozoospermia and male infertility.

Human reproduction open·2026

Edge Preserved U-Net for chromosome edge detection.

Computational biology and chemistry·2026

A Novel SLC25A4 Variant Causing Mitochondrial Dysfunction, Myopathy and Cardiomyopathy: A Functional and Molecular Characterization.

International journal of molecular sciences·2026

Circadian Disruption Is Associated with Elevated Whole-Semen mtDNA Copy Number and Implicates CRY1 as a Candidate Regulator in Humans and Mice.

International journal of molecular sciences·2026

A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease.

Cell metabolism·2026

Ataxin-2 regulates the synaptonemal complex to ensure chromosome pairing during female meiosis.

Genetics·2026

Related Experiment Videos

Unraveling heterochromatin

Related Concept Videos

Protocol for CRISPR genome editing in S. cerevisiae using PCR-based guide insertion.

Tandem bromodomains of BRD4 cooperatively read poly-acetylated nucleosomes to enhance chromatin engagement and regulate breast cancer phenotypes.

Discovery of Small-Molecule Antagonists of PHF1 and 19 Demonstrates the Ligandability of PRC2 Accessory Proteins.

Rapid CRISPR-Cas9 Genome Editing in S. cerevisiae.

Chromatin stability safeguards mitochondrial homeostasis and prevents mTORC1 hyperactivation.

HMGN1 and HMGN2 are recruited to acetylated and histone variant H2A.Z-containing nucleosomes to regulate chromatin state and transcription.

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection.

hnRNPK condensates facilitate enhancer-promoter looping and RNA polymerase II recruitment.

Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer's disease.

Prevalence and chronology of colibactin-associated mutational processes and their microbiome spectra in Japanese colorectal cancer.

HIPK4 is a novel gene associated with teratozoospermia and male infertility.

Edge Preserved U-Net for chromosome edge detection.

A Novel SLC25A4 Variant Causing Mitochondrial Dysfunction, Myopathy and Cardiomyopathy: A Functional and Molecular Characterization.

Circadian Disruption Is Associated with Elevated Whole-Semen mtDNA Copy Number and Implicates CRY1 as a Candidate Regulator in Humans and Mice.

A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease.

Ataxin-2 regulates the synaptonemal complex to ensure chromosome pairing during female meiosis.

Related Experiment Videos

Unraveling heterochromatin

Related Concept Videos

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