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[Discoloration of teeth by drugs]
M E de Wit1, B H Stricker, A J Porsius
1Bureau Bijwerkingen Geneesmiddelen, Farmacotherapie, rijksuniversiteit te Utrecht.
Nederlands Tijdschrift Voor Tandheelkunde
|January 1, 1996
Abstract:
Since 1979 the Dutch Centre for Monitoring of Adverse Reactions to Drugs received 37 reports of tooth discoloration, attributed to the use of drugs. It concerned sixteen males and 21 females with an average age of respectively twelve and 26 years. Most cases were attributed to the use of amoxicillin (n = 16) and doxycycline or minocycline (n = 7). Pseudo-discolorations are chiefly caused by antimicrobial agents, possibly by chromogenic precipitates in the pellicle or by overgrowth with chromogenic micro-organisms.