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Rasmussen's encephalitis: a role for autoimmune cytotoxic T lymphocytes
Jan Bauer1, Christian G Bien, Hans Lassmann
1Brain Research Institute, Division of Neuroimmunology, University of Vienna, Vienna, Austria.
Current Opinion in Neurology
|March 30, 2002
Abstract:
The present review describes advances in Rasmussen's encephalitis (also known as Rasmussen's syndrome), an unihemispheric intractable epileptic disease with persistent inflammation. Specific attention is given to the recent recognition of cytotoxicity by CD8+/granzyme-B-positive T lymphocytes as a new pathogenic mechanism of neuronal damage.