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Persimmon bezoars: a successful combined therapy
Jaume Gayà1, Lluis Barranco, Alfred Llompart
1Endoscopy Unit, Gastroenterology Department, Son Dureta Hospital, Palma (Mallorca), Spain.
Gastrointestinal Endoscopy
|March 30, 2002
Summary
This study introduces a new combination therapy for persimmon phytobezoars, achieving high success rates. While safe and effective, caution is advised regarding potential intestinal obstruction from large fragments.
Area of Science:
- Gastroenterology
- Endoscopic procedures
Background:
- Persimmon phytobezoars (diospyrobezoars) present management challenges.
- Existing treatments including surgical, endoscopic, and pharmacologic options have variable success rates.
Purpose of the Study:
- To describe the experience with a novel combination therapy for persimmon phytobezoar management.
Main Methods:
- A cohort of 10 patients (7 men, 3 women; mean age 46.4 years) received treatment.
- The therapy involved a fragmentation technique using a large polypectomy snare followed by administration of cellulase, cysteine, and metoclopramide.
Main Results:
- Successful resolution of the phytobezoar was achieved in 8 out of 10 patients.
- Two patients experienced complications, specifically intestinal obstruction.
Conclusions:
- The combined therapy demonstrates safety and high efficacy for persimmon phytobezoar treatment.
- Clinical observation suggests caution is necessary due to the risk of intestinal obstruction if large fragments pass the pylorus.
- Further extensive studies are warranted to validate these findings.