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Related Experiment Videos

Typhlitis in an immunocompromised patient.

S De Laere1, J J De Waele, B De Hemptinne

  • 1Department of Surgery, Gent University Hospital, Gent, Belgium.

Acta Chirurgica Belgica
|April 3, 2002
PubMed
Summary
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A young man undergoing treatment for acute lymphatic leukaemia developed right lower quadrant pain, mimicking appendicitis. Computed tomography revealed neutropenic enterocolitis (typhlitis) as the cause.

Area of Science:

  • Oncology
  • Gastroenterology
  • Radiology

Background:

  • Acute lymphatic leukaemia (ALL) is a hematologic malignancy requiring intensive treatment.
  • Neutropenia, a common side effect of ALL therapy, increases infection risk.
  • Abdominal pain in neutropenic patients warrants thorough investigation to rule out serious complications.

Observation:

  • A young male patient with diagnosed ALL presented with acute right lower quadrant abdominal pain.
  • Clinical presentation was initially suggestive of acute appendicitis.
  • Computed tomography (CT) scan of the abdomen was performed for diagnostic evaluation.

Findings:

  • CT scan demonstrated findings consistent with neutropenic enterocolitis, also known as typhlitis.
  • Typhlitis is an inflammatory condition of the bowel frequently seen in neutropenic patients.

Related Experiment Videos

  • The imaging findings helped differentiate typhlitis from appendicitis.

    • Implications:

    • This case highlights the importance of considering typhlitis in neutropenic patients presenting with abdominal pain.
    • Early diagnosis and appropriate management of typhlitis are crucial to prevent complications.
    • Radiological imaging plays a vital role in the accurate diagnosis of neutropenic enterocolitis.