Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hepatitis C and pregnancy].

L Alric1, N Costedoat, J C Piette

  • 1Service de médecine interne, pavillon Dieulafoy, hôpital Purpan, CHU, place du Docteur-Baylac, 31057 Toulouse, France. alric.L@chu-toulouse.fr

La Revue De Medecine Interne
|April 4, 2002
PubMed
Summary

Hepatitis C virus (HCV) infection in pregnancy is better understood, with vertical transmission rates around 6%. Careful follow-up of mothers and infants is crucial for managing perinatal HCV infection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Nasal septal perforation and systemic disease].

La Revue de medecine interne·2002
Same author

[Rupture of ascending aortic aneurysm revealing Takayasu's arteritis].

Archives des maladies du coeur et des vaisseaux·2002
Same author

[Kidney, lupus and pregnancy].

La Revue de medecine interne·2002
Same author

[ANCA associated glomerulonephritis related to benzylthiouracil].

La Revue de medecine interne·2002
Same author

[Neurological manifestations of Behçet's disease].

Revue neurologique·2002
Same author

Plasma exchange and interferon-alpha pharmacokinetics in patients with hepatitis C virus-associated systemic vasculitis.

Nephron·2002

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Maternal-Fetal Medicine

Background:

  • Antenatal screening for Hepatitis C virus (HCV) is recommended for women with risk factors.
  • Viral replication confirmation via PCR is necessary for pregnant women with anti-HCV antibodies.
  • Pregnancy management and delivery modes are generally unaffected by HCV infection alone.

Purpose of the Study:

  • To elucidate the natural course of Hepatitis C virus (HCV) infection during pregnancy.
  • To determine the prevalence and factors influencing mother-to-child transmission of HCV.

Main Methods:

  • Review of existing literature on HCV in pregnancy.
  • Analysis of vertical transmission rates in HCV-monoinfected and HIV-coinfected women.
  • Discussion of screening protocols for infants born to HCV-positive mothers.

Main Results:

  • HCV vertical transmission rates are approximately 6% in HCV-monoinfected women and 15% in HIV-coinfected women.
  • Infants born to HCV-positive mothers require HCV marker screening at 18 months postpartum.
  • Pregnancy is generally permissible for women with HCV due to low vertical transmission rates.

Conclusions:

  • Close monitoring of both mothers and newborns is essential for pregnancies affected by HCV.
  • Long-term follow-up of infants is necessary to evaluate the outcomes of perinatal HCV infection.
  • Antiviral treatment for HCV before pregnancy should be considered given new therapeutic strategies.

Related Experiment Videos