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Randomized clinical trials in rectal and anal cancer
Aviram Nissan1, Michael I Dangelica, Margo C Shoup
1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Surgical Oncology Clinics of North America
|April 4, 2002
Abstract:
Treatment of rectal cancer has changed dramatically over the past two decades. Radical surgery alone for resectable rectal cancer has been replaced by combined modality therapy. Interest in optimizing sphincter preservation and quality of life motivated surgeons to seek less radical surgery without compromising oncologic principles.