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The message and the messenger: delivering RNA in neurons
Kenneth S Kosik1, Anna M Krichevsky
1Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. kosik@rics.bwh.harvard.edu
Abstract:
Synaptic plasticity results in enduring changes in synaptic function. Localized protein synthesis is part of this process. Kosik and Krichevsky describe how a dynamic macromolecular structure, the RNA granule, may be a key element contributing to changes in protein production leading to synaptic plasticity.
Keywords:
Non-programmatic